Cristobalina Mayorga Selected Research

Immunotherapy

3/2024	Nasal allergen-neutralizing antibodies correlate closely with tolerated intranasal allergen challenge dose following grass pollen subcutaneous immunotherapy in patients with local allergic rhinitis.
1/2022	Transcriptional changes in dendritic cells underlying allergen specific induced tolerance in a mouse model.
1/2022	Methylation changes induced by a glycodendropeptide immunotherapy and associated to tolerance in mice.
11/2021	Immunomodulatory Response of Toll-like Receptor Ligand-Peptide Conjugates in Food Allergy.
11/2021	Role of nanostructures in allergy: Diagnostics, treatments and safety.
11/2019	Glycosylated nanostructures in sublingual immunotherapy induce long-lasting tolerance in LTP allergy mouse model.
1/2018	Immunotherapy with Native Molecule rather than Hypoallergenic Variant of Pru p 3, the Major Peach Allergen, Shows Beneficial Effects in Mice.
1/2017	LPS promotes Th2 dependent sensitisation leading to anaphylaxis in a Pru p 3 mouse model.
4/2011	Local allergic rhinitis: allergen tolerance and immunologic changes after preseasonal immunotherapy with grass pollen.

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Cristobalina Mayorga Research Topics

Disease

70	Hypersensitivity (Allergy) 01/2024 - 01/2002
18	Anaphylaxis (Anaphylactic Shock) 01/2023 - 07/2002
15	Drug Hypersensitivity (Drug Allergy) 11/2023 - 05/2008
13	Immediate Hypersensitivity 04/2024 - 02/2010
11	Food Hypersensitivity (Food Allergy) 01/2024 - 07/2012
9	Allergic Rhinitis 03/2024 - 04/2007
8	Urticaria (Hives) 01/2021 - 02/2003
6	Angioedema 01/2020 - 08/2013
5	Exanthema (Rash) 01/2021 - 08/2007
5	Rhinitis 01/2021 - 04/2007
4	COVID-19 12/2022 - 11/2020
3	Asthma (Bronchial Asthma) 11/2020 - 05/2006
3	Multiple Sclerosis 07/2012 - 06/2005
2	Infections 01/2022 - 06/2017
2	Delayed Hypersensitivity (Hypersensitivity, Type IV) 01/2022 - 01/2016
2	Seasonal Allergic Rhinitis (Hay Fever) 01/2020 - 01/2020
2	Drug-Related Side Effects and Adverse Reactions 01/2020 - 12/2011
2	Blister (Bulla) 07/2003 - 01/2002
1	Bacterial Infections (Bacterial Infection) 03/2024
1	Rosacea (Acne Rosacea) 07/2022
1	Convalescence 01/2022
1	Lung Neoplasms (Lung Cancer) 01/2020
1	type 2C Congenital disorder of glycosylation 01/2020
1	Aspirin-Induced Asthma 01/2020

Drug/Important Bio-Agent (IBA)

34	Immunoglobulin E (IgE)IBA 01/2024 - 07/2002
21	AllergensIBA 03/2024 - 04/2007
18	Amoxicillin (Wymox)FDA LinkGeneric 04/2024 - 10/2006
12	Anti-Bacterial Agents (Antibiotics)IBA 03/2024 - 05/2011
12	Proteins (Proteins, Gene)FDA Link 01/2023 - 02/2003
10	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 01/2020 - 08/2009
9	Penicillins (Penicillin)FDA Link 06/2022 - 11/2003
9	beta-LactamsIBA 01/2021 - 01/2006
9	Cephalosporins (Cephalosporin Antibiotics)IBA 12/2020 - 01/2002
7	AntigensIBA 01/2022 - 02/2003
7	LactamsIBA 10/2021 - 05/2011
6	Clavulanic Acid (Potassium Clavulanate)FDA LinkGeneric 03/2024 - 02/2010
6	Biomarkers (Surrogate Marker)IBA 11/2023 - 08/2015
5	VaccinesIBA 12/2022 - 02/2003
5	Dipyrone (Metamizole)IBA 03/2016 - 03/2013
4	LipidsIBA 07/2022 - 01/2018
4	Peptides (Polypeptides)IBA 11/2021 - 10/2019
4	Dendrimers (Dendrons)IBA 01/2020 - 04/2015
4	AntibodiesIBA 04/2015 - 07/2002
3	Immunoglobulin G (IgG)IBA 01/2023 - 02/2003
3	COVID-19 VaccinesIBA 12/2022 - 01/2022
3	EpitopesIBA 10/2022 - 08/2005
3	Penicillin G (Benzylpenicillin)FDA LinkGeneric 06/2022 - 01/2015
3	EnzymesIBA 06/2022 - 08/2015
3	beta Lactam AntibioticsIBA 02/2014 - 01/2006
2	lipid transfer protein (glycolipid transfer protein)IBA 01/2024 - 11/2021
2	BNT162 VaccineIBA 01/2022 - 01/2022
2	Toll-Like Receptor AgonistsIBA 11/2021 - 01/2013
2	Cefuroxime (Zinacef)FDA LinkGeneric 12/2020 - 07/2002
2	abacavir (Ziagen)FDA Link 01/2020 - 01/2019
2	Histamine (Histamine Dihydrochloride)FDA Link 01/2017 - 01/2016
2	FluoroquinolonesIBA 06/2016 - 12/2013
2	Moxifloxacin (Avelox)FDA Link 06/2016 - 01/2013
2	PyrazolonesIBA 03/2016 - 01/2016
2	Ibuprofen (Motrin)FDA LinkGeneric 01/2016 - 03/2013
2	Acetaminophen (Paracetamol)FDA LinkGeneric 01/2016 - 03/2013
2	HLA-DR alpha-ChainsIBA 01/2016 - 01/2015
2	HaptensIBA 01/2016 - 11/2009
2	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 01/2016 - 08/2015
2	Diclofenac (SR 38)FDA LinkGeneric 01/2016 - 08/2015
2	CytokinesIBA 01/2014 - 05/2006
2	Interferon-betaIBA 06/2005 - 08/2002
1	Neutralizing AntibodiesIBA 03/2024
1	Silicon Dioxide (Silica)FDA LinkGeneric 01/2023
1	diphenylthiosulfinate (DPTS)IBA 06/2022
1	hypoxanthine arabinoside (ara-H)IBA 04/2022
1	RNA (Ribonucleic Acid)IBA 01/2022
1	7-anilinocoumarin-4-acetic acidIBA 01/2022
1	HLA-DRB3 Chains (HLA DRB3)IBA 01/2022
1	Excipients (Suspending Agents)IBA 01/2022
1	mRNA VaccinesIBA 01/2022
1	Messenger RNA (mRNA)IBA 01/2022
1	PectinsIBA 12/2021
1	Cefazolin (Ancef)FDA LinkGeneric 12/2021
1	Toll-Like Receptors (Toll-Like Receptor)IBA 11/2021
1	LigandsIBA 11/2021
1	8-hydroxyadenineIBA 11/2021
1	indoleIBA 11/2021
1	Pru p 3 allergenIBA 11/2021
1	Carrier Proteins (Binding Protein)IBA 11/2021
1	Cefadroxil (Duricef)FDA LinkGeneric 12/2020
1	Hexachlorobenzene (HCB)IBA 12/2020
1	Profilins (Profilin)IBA 12/2020
1	Adrenal Cortex Hormones (Corticosteroids)IBA 11/2020
1	TabletsIBA 11/2020
1	Immunodominant EpitopesIBA 01/2020
1	Arachidonic Acid (Vitamin F)IBA 01/2020
1	Immunotoxins (Immunotoxin)IBA 01/2020
1	Lapatinib (GW572016)FDA Link 01/2020
1	Coloring Agents (Dyes)IBA 01/2020

Therapy/Procedure

9	Immunotherapy 03/2024 - 04/2011
7	Therapeutics 05/2021 - 08/2002
3	Precision Medicine 12/2022 - 11/2020
1	Injections 01/2022
1	Immunomodulation 12/2021
1	Off-Label Use 11/2020